Appleton United Lacrosse was founded in 2003 and is a member of the WIAA in the Fox Valley Association (FVA) conference. The high school boy's lacrosse program is a varsity sport under the purview of Appleton East. The team is a cooperative of student-athletes from Appleton East, Appleton North, Appleton West, Fox Valley Lutheran, Hortonville, Ripon, Waupaca, Wild Rose, and Xavier high schools.